Breast Cancer and Paw Paw

Extracts of paw paw (Asimina triloba, Annonaceae family) have strong anti-cancer activity. The paw paw is a small tree with edible fruit native to eastern North America. The annonaceous acetogenins ... more

Breast Cancer and Iodine

Fucoidan refers to a type of polysaccharide which contains substantial percentages of L-fucose and sulfate ester groups, mainly derived from brown seaweed. Brown seaweeds were found to prevent the binding ... more

Menopausal Symptoms

Extracts of the rootstock of Black cohosh contain biologically active constituents as triterpene glycosides (actein, cimicifugoside, deoxyacetein), isoferulic acid and alkaloids (n-methylcytisine). Recent data has demonstrated that Black Cohosh may ... more

Cancer, Stress-Reduction and Meditation

The following studies suggest that meditation can decrease the likelihood of recurrence of cancer. A mindfulness meditation program was effective in decreasing mood disturbance and stress symptoms in both male ... more

Breast Cancer, Exercise, and Diet

Women who are both physically active, exercising for 30 minutes daily (walking) 6 days a week and who consume 6 servings of fruits and vegetables daily can reduce their risk ... more

The Birth Control Pill and Breast Cancer Risk

The birth control pill (BCP) or oral contraceptives, when used before age 20, significantly increase risk of early-onset breast cancer (diagnosed before age 36). If the BCP is used consistently ... more

Breast Cancer, Insulin, and IGF-1

Studies have shown an increase in breast cancer risk among women who have elevated levels of testosterone, reduced levels of sex hormone-binding globulin (SHBG), and therefore elevated levels of bioavailable ... more

Selenium with Chemotherapy

Selenium sensitizes MCF-7 breast cancer cells to doxorubicin-induced apoptosis through modulation of phospho-Akt and its downstream substrates. Effect of selenium in combination with Adriamycin or Taxol on several different ... more

Miso Protects During Radiation Therapy

Animal studies demonstrate that fermented miso protects against the effects of radiation.   Radioprotective effects of miso (fermented soy bean paste) against radiation in B6C3F1 mice: increased small intestinal crypt survival, crypt ... more

Melatonin with Chemotherapy

When given with the chemotherapy drug Doxorubicin, which can damage heart muscle, melatonin protects heart cells from damage by raising glutathione levels and stimulating catalase activity. (Catalase is an enzyme ... more

Green Tea (Theanine) with Chemotherapy

In a study on mice with ovarian cancer, theanine (found in green tea) enhanced the inhibitory effect of the chemotherapy drug Doxorubicin on tumor growth and increased the Doxorubicin concentration ... more

Genetic Testing and Chemotherapy Selection

Prospective Multicenter Study of the Impact of the 21-Gene Recurrence Score Assay on Medical Oncologist and Patient Adjuvant Breast Cancer Treatment Selection. Ki67 expression and docetaxel efficacy in patients ... more

Breast Cancer and Tamoxifen

Some selective serotonin reuptake inhibitor (SSRI) antidepressants, such as Paxil (Paroxetine), reduce tamoxifen's effectiveness by inhibiting its bioactivation by cytochrome P450 2D6 (CYP2D6). Paroxetine use during tamoxifen treatment is associated ... more

Antioxidants during Chemotherapy and Radiation

Fifty human clinical randomized or observational trials have been conducted, involving 8,521 patients using beta-carotene; vitamins A, C, and E; selenium; cysteine; B vitamins; vitamin D3; vitamin K3; and glutathione ... more

Breast Cancer and Sunscreens

Ultraviolet sunscreens are increasingly used to protect from ultraviolet radiation and skin cancer. They are often added to cosmetics and other products for light stability. However, many of the chemicals ... more

Breast Cancer and Phthalates

Phthalates are ubiquitous, carcinogenic estrogenic chemicals that contaminate food, indoor air, soil, sediment and drinking water. They are added to plastics to make them soft, to polyvinyl chloride (PVC) products ... more

Breast Cancer and PCBs

Polychlorinated Biphenyls are synthetic chlorinated hydrocarbon compounds whose commercial production started in the thirties. They have been widely used in the electro-technical industry. Mammals continue to be exposed to the ... more

Breast Cancer and Parabens

The parabens are phenolic compounds used as preservatives in 22,000 cosmetics, toothpaste, shampoos, conditioners etc. They include methylparaben, ethylparaben, propylparaben, butylparaben, isopropylparaben and isobutylparaben. They all weakly stimulate growth of ... more

Breast Cancer and Bisphenol A

Bisphenol A (BPA) is used in manufacturing a wide range of chemical products which include epoxy resins and polycarbonate (hard plastics). BPA increases the cell proliferation activity of human breast ... more

Sulforaphane and Breast Cancer

Sulforaphane causes epigenetic repression of hTERT expression in human breast cancer cell lines. Sulforaphane, a dietary component of broccoli/broccoli sprouts, inhibits breast cancer stem cells. Putative chemopreventive molecules can ... more

Mekabu Seaweed Inhibits Breast Cancer

Intracellular signalling in the induction of apoptosis in a human breast cancer cell line by water extract of Mekabu.

Breast Cancer, Turmeric, and Curcumin

Curcumin, a derivative of the Indian spice, turmeric (used in curry powder) is active against many forms of cancer including leukemia and lymphoma, gastrointestinal cancers, genitourinary cancers, breast cancer, ovarian ... more

Breast Cancer, Grape Seed Extract and Resveratrol

Grape seeds contain high levels of procyanidin B dimers that act as both anti-oxidants and aromatase inhibitors (which suppress estrogen production and inhibit growth of estrogen dependent breast cancer). Grape ... more

Breast Cancer and Watercress

Aberrant overexpression of matrix metalloproteinases, including metalloproteinase-9, is associated with increased invasive potential in cancer cell lines. Studies demonstrate that extracts of broccoli and watercress suppressed MMP-9 activity and invasiveness in a ... more

Breast Cancer and Vegan Diet

Approximately 30-40% of all of cancers can be prevented with a healthy lifestyle and diet. Too little fiber, the intake of red meat and too little Omega-3 fats with too ... more

Soy Reduces Breast Cancer Risk

Confused about soy?  The research on its benefits continues to pile up, including studies on women. A 2016 review of each of the major research areas involving soy concludes that it reduces ... more

Breast Cancer and Pomegranate

Pomegranate extracts inhibit the growth of breast, prostate, colon and lung cancer cells in culture. In animal studies, oral consumption of pomegranate extract inhibited growth of lung, skin, colon and ... more

Breast Cancer and Olive Oil

Extra virgin olive oil inhibits growth of breast cancer tumors that are positive for HER2neu. Extra-virgin olive oil polyphenols inhibit HER2 (erbB-2)-induced malignant transformation in human breast epithelial cells: relationship ... more