Extracts of the rootstock of Black cohosh contain biologically active constituents as triterpene glycosides (actein, cimicifugoside, deoxyacetein), isoferulic acid and alkaloids (n-methylcytisine). Recent data has demonstrated that Black Cohosh may ... more
The following studies suggest that meditation can decrease the likelihood of recurrence of cancer. A mindfulness meditation program was effective in decreasing mood disturbance and stress symptoms in both male ... more
Women who are both physically active, exercising for 30 minutes daily (walking) 6 days a week and who consume 6 servings of fruits and vegetables daily can reduce their risk ... more
The birth control pill (BCP) or oral contraceptives, when used before age 20, significantly increase risk of early-onset breast cancer (diagnosed before age 36). If the BCP is used consistently ... more
Studies have shown an increase in breast cancer risk among women who have elevated levels of testosterone, reduced levels of sex hormone-binding globulin (SHBG), and therefore elevated levels of bioavailable ... more
Selenium sensitizes MCF-7 breast cancer cells to doxorubicin-induced apoptosis through modulation of phospho-Akt and its downstream substrates. Effect of selenium in combination with Adriamycin or Taxol on several different ... more
Animal studies demonstrate that fermented miso protects against the effects of radiation. Radioprotective effects of miso (fermented soy bean paste) against radiation in B6C3F1 mice: increased small intestinal crypt survival, crypt ... more
When given with the chemotherapy drug Doxorubicin, which can damage heart muscle, melatonin protects heart cells from damage by raising glutathione levels and stimulating catalase activity. (Catalase is an enzyme ... more
In a study on mice with ovarian cancer, theanine (found in green tea) enhanced the inhibitory effect of the chemotherapy drug Doxorubicin on tumor growth and increased the Doxorubicin concentration ... more
Prospective Multicenter Study of the Impact of the 21-Gene Recurrence Score Assay on Medical Oncologist and Patient Adjuvant Breast Cancer Treatment Selection. Ki67 expression and docetaxel efficacy in patients ... more
Some selective serotonin reuptake inhibitor (SSRI) antidepressants, such as Paxil (Paroxetine), reduce tamoxifen's effectiveness by inhibiting its bioactivation by cytochrome P450 2D6 (CYP2D6). Paroxetine use during tamoxifen treatment is associated ... more
Fifty human clinical randomized or observational trials have been conducted, involving 8,521 patients using beta-carotene; vitamins A, C, and E; selenium; cysteine; B vitamins; vitamin D3; vitamin K3; and glutathione ... more
Mercuric chloride exerts an estrogenic effect through binding to the estrogen receptor that can cause human breast cancer cells to proliferate. The heavy metals iron, nickel, chromium, zinc, cadmium, mercury, ... more
Ultraviolet sunscreens are increasingly used to protect from ultraviolet radiation and skin cancer. They are often added to cosmetics and other products for light stability. However, many of the chemicals ... more
Phthalates are ubiquitous, carcinogenic estrogenic chemicals that contaminate food, indoor air, soil, sediment and drinking water. They are added to plastics to make them soft, to polyvinyl chloride (PVC) products ... more
Polychlorinated Biphenyls are synthetic chlorinated hydrocarbon compounds whose commercial production started in the thirties. They have been widely used in the electro-technical industry. Mammals continue to be exposed to the ... more
The parabens are phenolic compounds used as preservatives in 22,000 cosmetics, toothpaste, shampoos, conditioners etc. They include methylparaben, ethylparaben, propylparaben, butylparaben, isopropylparaben and isobutylparaben. They all weakly stimulate growth of ... more
Bisphenol A (BPA) is used in manufacturing a wide range of chemical products which include epoxy resins and polycarbonate (hard plastics). BPA increases the cell proliferation activity of human breast ... more
Sulforaphane causes epigenetic repression of hTERT expression in human breast cancer cell lines. Sulforaphane, a dietary component of broccoli/broccoli sprouts, inhibits breast cancer stem cells. Putative chemopreventive molecules can ... more
Intracellular signalling in the induction of apoptosis in a human breast cancer cell line by water extract of Mekabu. http://www.ncbi.nlm.nih.gov/pubmed/15864698
Curcumin, a derivative of the Indian spice, turmeric (used in curry powder) is active against many forms of cancer including leukemia and lymphoma, gastrointestinal cancers, genitourinary cancers, breast cancer, ovarian ... more
Grape seeds contain high levels of procyanidin B dimers that act as both anti-oxidants and aromatase inhibitors (which suppress estrogen production and inhibit growth of estrogen dependent breast cancer). Grape ... more
Aberrant overexpression of matrix metalloproteinases, including metalloproteinase-9, is associated with increased invasive potential in cancer cell lines. Studies demonstrate that extracts of broccoli and watercress suppressed MMP-9 activity and invasiveness in a ... more
Approximately 30-40% of all of cancers can be prevented with a healthy lifestyle and diet. Too little fiber, the intake of red meat and too little Omega-3 fats with too ... more
Confused about soy? The research on its benefits continues to pile up, including studies on women. A 2016 review of each of the major research areas involving soy concludes that it reduces ... more
Pomegranate extracts inhibit the growth of breast, prostate, colon and lung cancer cells in culture. In animal studies, oral consumption of pomegranate extract inhibited growth of lung, skin, colon and ... more
Extra virgin olive oil inhibits growth of breast cancer tumors that are positive for HER2neu. Extra-virgin olive oil polyphenols inhibit HER2 (erbB-2)-induced malignant transformation in human breast epithelial cells: relationship ... more
The medicinal mushrooms - maitake, shitake, reishi (Ganoderma), coriolus and oyster have anti-tumour and immune strengthening effects. Maitake D-fraction caused regression or significant symptom improvement in 58.3 percent of liver cancer ... more
Epigallocatechin-3-gallate (EGCG), the main constituent of green tea, was found to stabilize p27Kip1 (a gene that regulates cell division, arresting cells in the G1 phase) levels in breast cancer. Thus, ... more
In a laboratory setting diallyl disulphide, a component in garlic, inhibits the proliferation of MCF-7 breast cancer cells and causes cell death (apoptosis) of MCF-7 cells. Garlic may help to ... more